Pharmacy Policy Updates

Blue Cross Blue Shield of North Dakota (BCBSND) continually develops and revises pharmacy policies in response to rapidly changing pharmaceutical requirements. Our commitment is to update the provider community as pharmacy policies are adopted and/or revised.

Medicaid Expansion Updates

Note: There may be corresponding policies for our Commercial lines of business.

The following Medicaid Expansion prior authorization medical drug policies have revisions effective March 1, 2026:

  • Alglucosidase alfa (Lumizyme) and Avalglucosidase alfa-ngpt (Nexviazyme)
  • Alpha1-Proteinase Inhibitors
  • Cipaglucosidase alfa-atga (Pombiliti)
  • Lovotibeglogene autotemcel (Lyfgenia)
  • Lurbinectedin (Zepzelca)
  • Obinutuzumab (Gazyva)
  • Programmed Death Receptor (PD-1)/ Programmed Death-Ligand (PD-L1) Blocking Antibodies
  • Tocilizumab
  • Treatment of Gaucher Disease
  • Ustekinumab IV

The following Medicaid Expansion medical drug policies were reviewed and have no changes:

  • Abatacept (Orencia) IV
  • ADAMTS13, recombinant-krhn (Adzynma)
  • Amivantamab-vmjw (Rybrevant)
  • Chimeric Antigen Receptor Therapy for Leukemia and Lymphoma
  • Chimeric Antigen Receptor Therapy for Multiple Myeloma
  • Cipaglucosidase alfa-atga (Pombiliti)
  • Ibalizumab-uiyk (Trogarzo)
  • Imetelstat (Rytelo)
  • Immune Globulin Therapy
  • Infliximab
  • Isatuximab-irfc (Sarclisa)
  • Luspatercept (Reblozyl)
  • Rozanolixizumab-noli (Rystiggo)
  • Teplizumab-mzwv (Tzield)

The following Medicaid Expansion medical drug policy has a coding update effective Jan. 1, 2026:

  • Gonadotropin Releasing Hormones (GnRHs) Analogs

Medicaid Expansion and Commercial Updates

The following Medicaid Expansion and Commercial medical drug policy has a coding update effective Jan. 1, 2026:

  • Implantable Hormone Replacement Pellets

Commercial Updates

Medical Pharmacy

The following Commercial prior authorization medical drug policies are new and effective March 1, 2026:

*see www.gatewaypa.com/policydisplay/52 on or after March 1, 2026

  • Blenrep (belantamab mafodotin-blmf)
  • Itvisma (onasemnogene abeparvovec-brve)

Retail Pharmacy

The following retail pharmacy Utilization Management (UM) program is effective March 1, 2026:

*see www.myprime.com/en/forms.html on or after March 1, 2026

  • Anzupgo Prior Authorization Quantity Limit Program
    • Commercial and HIM Formularies

The following Commercial medical drug policies have coding updates effective Jan. 1, 2026:

New Code
Jan. 1, 2026

Brand Name (Generic Name)

C9308

Kyxata (carboplatin)

C9307

Lynozyfic (linvoseltamab-gcpt)

J7299

Contraceptive Management


The following retail pharmacy administrative actions occurred from Nov. 24, 2025, to Dec. 29, 2025:

UM Program Name

Program Type

Formulary

Effective Date

Summary of Changes

Ophthalmic Prostaglandins

Quantity Limit; Step Therapy

Commercial, HIM, NetResults

Dec. 29, 2025

Addition of Omlonti

Self-Administered Oncology Agents

Prior Authorization; Quantity Limit

Commercial, HIM, NetResults

Dec. 29, 2025

Addition of Hyrnuo

Interleukin (IL-1) Inhibitors

Prior Authorization; Quantity Limit

Commercial, HIM, NetResults

Dec. 22, 2025

Addition of Otezla XR, Rhapsido, and Tyruko to contraindicated table

Lupus

Prior Authorization; Quantity Limit

Commercial, HIM, NetResults

Dec. 22, 2025

Addition of Otezla XR, Rhapsido, and Tyruko to contraindicated table

Spevigo (spesolimab-sbzo)

Prior Authorization; Quantity Limit

Commercial, HIM, NetResults

Dec. 22, 2025

Addition of Otezla XR, Rhapsido, and Tyruko to contraindicated table

Multiple Sclerosis Agents

Prior Authorization; Quantity Limit

Commercial, HIM, NetResults

Dec. 22, 2025

Addition of asterisk to Mavenclad in FDA table and preferred agent table to identify availability of generic; auto-roll-in of new generic therapy pack

Self-Administered Oncology Agents

Prior Authorization; Quantity Limit

Commercial, HIM, NetResults

Dec. 15, 2025

Addition of Komzifti

Atypical Antipsychotics

Quantity Limit; Step Therapy

Commercial, HIM, NetResults

Dec. 8, 2025

Removed Clozapine ODT as a step target due to generic only availability

Pulmonary Arterial Hypertension

Prior Authorization; Quantity Limit

Commercial, HIM, NetResults

Dec. 8, 2025

Addition of new Tyvaso DPI strengths to PA and QL Tables

Dry Eye Disease

Prior Authorization; Quantity Limit

NetResults

Dec. 1, 2025

Removed auto-roll-in single-use Restasis NDCs (00480407630 & 00480407660) from Restasis multidose QL target entry

Self-Administered Oncology Agents

Prior Authorization; Quantity Limit

Commercial, HIM, NetResults

Dec. 1, 2025

Addition of Pazopanib 400 mg

Biologic Immunomodulators

Prior Authorization; Quantity Limit

Commercial, HIM, NetResults

Dec. 1, 2025

Addition of Ustekinumab-aauz

Biologic Immunomodulators

Prior Authorization; Quantity Limit

Commercial, HIM, NetResults

Nov.24, 2025

Addition of Starjemza

Alternative Dosage Form

Prior Authorization; Quantity Limit

NetResults

Nov.24, 2025

Addition of Tonmya as target


The following retail pharmacy administrative actions will occur March 1, 2026:

UM Program Name

Program Type

Formulary

Summary of Changes

Biologic Immunomodulators OP2

Prior Authorization; Quantity Limit

Commercial, HIM, NetResults

Added Omvoh 200 mg/2mL syringe and pen to QL Target Agents