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Excision Repair Cross-Complementing Factor 1 (ERCC1) Analysis for Non-Small Cell Lung Cancer

Section: Laboratory
Effective Date: November 01, 2019
Revised Date: October 02, 2019
Last Reviewed: September 26, 2019

Description

The excision repair cross-complementing factor 1 (ERCC1) gene is an important and critical gene in the cell’s ability to repair damage to DNA.  ERCC1 plays a key role in the nucleotide excision repair of the DNA and has been shown to possibly play a role in the repair of the damage produced by the use of cisplatin and other platinum based chemotherapy drugs.

Criteria

ERCC1 analysis for non-small cell lung cancer (NSCLC) is considered experimental/investigational and therefore, non-covered because the safety and/or effectiveness of this service cannot be established by the available published peer-reviewed literature.

Procedure Codes

88341 88342 88360

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