ND Committee Review 
 Internal Medical Policy Committee 1-22-2020 Adopted new precertification policy 
 Internal Medical Policy Committee 1-13-2021 Annual review, no clinical content change 
 Internal Medical Policy Committee 7-22-2021 
- Revised
                         NCCN recommendations criteria; 
            
            and
 - Removed
                         Z85.72; 
            
            and
 - Added
                         diagnosis codes C86.0 and C86.1. 
        
        
 
 Internal Medical Policy Committee 7-21-2022 Annual review, no clinical content change 
 Internal Medical Policy Committee 11-29-2022 
- Removed
                         NCCN recommendations; 
            
            and
 - Added
                         this statement 'Pralatrexate (Folotyn) may be considered medically necessary for treatment of any of the current category 1 or 2A NCCN recommendations.'; 
            
            and
 - Updated
                         experimental/investigational statement; 
            
            and
 - Added
                         diagnosis code C84.7A 
        
        
 
 Internal Medical Policy Committee 11-15-2023 Annual review, no clinical content change 
                 Internal Medical Policy Committee 11-19-2024 
        
        Effective December 08, 2024