The use of relatively high doses of opioid antagonists under deep sedation or general anesthesia is a technique for opioid detoxification and is known as ultra-rapid detoxification. It is a potential alternative to standard detoxification that allows individuals to avoid the acute symptoms associated with initial detoxification. Ultra-rapid detoxification is used in conjunction with maintenance treatments, e.g., oral opioid antagonists and psychosocial support.
UROD is considered experimental/investigational and therefore non-covered as a clinical detoxification treatment because its effectiveness has not been established.
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